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Prescription Drugs > Analgesics > How They Work


Opioids work by attaching to receptors that are located on cells, many of which are in the brain. These receptors alter the way cells function. Once opioids attach to a receptor, pain messages are reduced and the feeling of pain is decreased.

When opioids are used properly, under the care of your doctor or other healthcare professional, they are usually effective at relieving pain. They may cause side effects such as drowsiness, nausea, vomiting, itching, headache, dry-mouth, sweating, weakness, and constipation. When opioids are misused or abused, in addition to side effects, they can cause more serious problems such as extremely slow breathing and death.
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